Dilution to a concentration of less than 600 micrograms/mL is unstable. CEFTRIAXONE (ROCEPHIN ®) - Intravenous (IV) Dilution. The amount and frequency of dosage for maintaining the serum uric acid just within the normal range is best determined by using the serum uric acid level as an index.
The initial infusion rate should not exceed 30 mg/min. Be sure to follow relevant directions on product labels and consult your Did you or will you purchase this product in-store or online?Where did you or where do you plan to purchase this product?Where did you or where do you plan to purchase this product?What factors influenced or will influence your purchase? There has been no clinical experience in the management of a patient who has taken massive amounts of allopurinol.Both allopurinol and oxypurinol are dialyzable; however, the usefulness of hemodialysis or peritoneal dialysis in the management of an overdose of allopurinol sodium for injection is unknown.The dosage of allopurinol sodium for injection to lower serum uric acid to normal or near-normal varies with the severity of the disease. The contents of each 50 mL vial should be dissolved with 25 mL of Sterile Water for Injection. Skin reactions can be severe and sometimes fatal.
Standard Dilutions [Amount of drug] [Infusion volume] [Infusion rate] [150 mg / 100 ml] [10 minutes] (Glass bottle or polyolefin container) [720 mg / 500 ml ] [See comments] [900 mg / 500 ml ] [See comments] (an inline 0.22 micron filter should be used). If anorexia, weight loss, or pruritus develop in patients on allopurinol, evaluation of liver function should be part of their diagnostic workup. Allopurinol reduces both the serum and urinary uric acid levels by inhibiting the formation of uric acid. The rate of the maintenance infusion may be increased to achieve effective arrhythmia suppression. Procainamide carries a 15% to 20% risk and hydralazine carries a 7% to 13% risk. administration of allopurinol sodium for injection were dose proportional in the dose range of 100 to 300 mg.
It is an inhibitor of xanthine oxidase, the enzyme responsible for the conversion of hypoxanthine to xanthine and of xanthine to uric acid, the end product of purine metabolism in man. There are isolated case reports of xanthine crystalluria in patients who were treated with oral allopurinol.The action of oral allopurinol differs from that of uricosuric agents, which lower the serum uric acid level by increasing urinary excretion of uric acid. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.WebMD does not provide medical advice, diagnosis or treatment.This survey is being conducted by the WebMD marketing sciences department.All information will be used in a manner consistent with the WebMD Normal subjects over 65 years of age show lower clearances (about 100 mL/hr/kg) than younger subjects (about 150 mL/hr/kg) and an increase in t1/2 from about 20 to 47 days. As a result, the concomitant administration of uricosuric agents decreases the inhibition of xanthine oxidase by oxypurinol and increases the urinary excretion of uric acid.Reports that the concomitant administration of allopurinol and thiazide diuretics contributed to increased allopurinol toxicity were reviewed; a causal mechanism or cause-and-effect relationship was not found. Amiodarone does not need to be protected from light during administration.After the first 24 hours, the maintenance infusion rate of 0.5 mg/min (720 mg/24 hours) should be continued utilizing a concentration of 1 to 6 mg/mL (Cordarone I.V. Acyclovir sodium is a white, crystalline powder with the molecular formula C8H10N5NaO3 and a molecular weight of 247.19.
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